A simple method for constructing E1- and E1/E4-deleted recombinant adenoviral vectors.
نویسندگان
چکیده
We previously developed a two-plasmid in vitro ligation method that did not require a recombination step to produce new recombinant E1- or E1/E3-deleted adenoviral vectors. In this study, we have modified the system to improve the simplicity of vector construction and, in addition, to allow for production of an E1/E4-deleted vector.
منابع مشابه
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ورودعنوان ژورنال:
- Human gene therapy
دوره 10 12 شماره
صفحات -
تاریخ انتشار 1999